Plant Breeders Use Old Sloppy “Natural” Process to Avoid Regulatory Stasis

(p. A11) What’s in a name?
A lot, if the name is genetically modified organism, or G.M.O., which many people are dead set against. But what if scientists used the precise techniques of today’s molecular biology to give back to plants genes that had long ago been bred out of them? And what if that process were called “rewilding?”
That is the idea being floated by a group at the University of Copenhagen, which is proposing the name for the process that would result if scientists took a gene or two from an ancient plant variety and melded it with more modern species to promote greater resistant to drought, for example.
“I consider this something worth discussing,” said Michael B. Palmgren, a plant biologist at the Danish university who headed a group, including scientists, ethicists and lawyers, that is funded by the university and the Danish National Research Foundation.
They pondered the problem of fragile plants in organic farming, came up with the rewilding idea, and published their proposal Thursday in the journal Trends in Plant Science.
. . .
The idea of restoring long-lost genes to plants is not new, said Julian I. Schroeder, a plant researcher at the University of California, Davis. But, wary of the taint of genetic engineering, scientists have used traditional breeding methods to cross modern plants with ancient ones until they have the gene they want in a crop plant that needs it. The tedious process inevitably drags other genes along with the one that is targeted. But the older process is “natural,” Dr. Schroeder said.
. . .
Researchers have previously crossbred wheat plants with traits found in ancient varieties, noted Maarten Van Ginkel, who headed such a program in Mexico at the International Maize and Wheat Improvement Center.
“We selected for disease resistance, drought tolerance,” he said. “This method works but it has drawbacks. You prefer to move only the genes you want.”
When Dr. Van Ginkel crossbred for traits, he did not look for the specific genes conferring those traits. But with the flood-resistant rice plants, researchers knew exactly which gene they wanted. Nonetheless, they crossbred and did not use precision breeding to alter the plants.
Asked why not, Dr. Schroeder had a simple answer — a complex maze of regulations governing genetically engineered crops. With crossbreeding, he said, “the first varieties hit the fields in a couple of years.”
And if the researchers had used precision breeding to get the gene into the rice?
“They would still be stuck in the regulatory process,” Dr. Schroeder said.

For the full story, see:
GINA KOLATA. “A Proposal to Modify Plants Gives G.M.O. Debate New Life.” The Wall Street Journal (Fri., MAY 29, 2015): A11.
(Note: ellipses added.)
(Note: the online version of the story has the date MAY 28, 2015.)

A Critical Mass Need to Be Motivated by the Telos of a Practice

(p. 227) The fact that some people are led into a practice in pursuit of goals that are external to the practice– money, fame, or what have you– need pose no threat to the integrity of the practice itself. So long as those goals do not penetrate the practice at all levels, those in pursuit of external goals will eventually drop out or be left behind or change their goals or be discredited by those in pursuit of a practice’s proper goals. However, if external goals do penetrate the practice at all levels, it becomes vulnerable to corruption. Practices are always developing and changing, and the direction that development takes will be determined by participants in the practice. Good practices encourage wise practitioners who in turn will care for the future of the practice.

Source:
Schwartz, Barry, and Kenneth Sharpe. Practical Wisdom: The Right Way to Do the Right Thing. New York: Riverhead Books, 2010.

A somewhat similar point is made in:
Diamond, Arthur M., Jr. “How Institutional Incentives and Constraints Affect the Progress of Science.” Prometheus 26, no. 3 (Sept. 2008): 231-239.

Physicists Accepting Theories Based on Elegance Rather than Evidence

(p. 5) Do physicists need empirical evidence to confirm their theories?
. . .
A few months ago in the journal Nature, two leading researchers, George Ellis and Joseph Silk, published a controversial piece called “Scientific Method: Defend the Integrity of Physics.” They criticized a newfound willingness among some scientists to explicitly set aside the need for experimental confirmation of today’s most ambitious cosmic theories — so long as those theories are “sufficiently elegant and explanatory.” Despite working at the cutting edge of knowledge, such scientists are, for Professors Ellis and Silk, “breaking with centuries of philosophical tradition of defining scientific knowledge as empirical.”
Whether or not you agree with them, the professors have identified a mounting concern in fundamental physics: Today, our most ambitious science can seem at odds with the empirical methodology that has historically given the field its credibility.

For the full commentary, see:
ADAM FRANK and MARCELO GLEISER. “Gray Matter; A Crisis at the Edge of Physics.” The New York Times, SundayReview Section (Sun., JUNE 7, 2015): 5.
(Note: ellipsis added.)
(Note: the date of the online version of the commentary is JUNE 5, 2015, and has the title “A Crisis at the Edge of Physics.”)

The controversial Nature article, mentioned above, is:
Ellis, George, and Joe Silk. “Scientific Method: Defend the Integrity of Physics.” Nature 516, no. 7531 (Dec. 18, 2014): 321-23.

Mathematician Says Mathematical Models Failed

The author of the commentary quoted below is a professor of mathematics at the Baltimore County campus of the University of Maryland.

(p. 4) . . . , in a fishery, the maximum proportion of a population earmarked each year for harvest must be set so that the population remains sustainable.

The math behind these formulas may be elegant, but applying them is more complicated. This is especially true for the Chesapeake blue crabs, which have mostly been in the doldrums for the past two decades. Harvest restrictions, even when scientifically calculated, are often vociferously opposed by fishermen. Fecundity and survival rates — so innocuous as algebraic symbols — can be difficult to estimate. For instance, it was long believed that a blue crab’s maximum life expectancy was eight years. This estimate was used, indirectly, to calculate crab mortality from fishing. Derided by watermen, the life expectancy turned out to be much too high; this had resulted in too many crab deaths being attributed to harvesting, thereby supporting charges of overfishing.
In fact, no aspect of the model is sacrosanct — tweaking its parameters is an essential part of the process. Dr. Thomas Miller, director of the Chesapeake Biological Laboratory at the University of Maryland Center for Environmental Science, did just that. He found that the most important factor for raising sustainability was the survival rate of pre-reproductive-age females. This was one reason, in 2008, after years of failed measures to increase the crab population, regulatory agencies switched to imposing restrictions primarily on the harvest of females.    . . .
The results were encouraging: The estimated population rose to 396 million in 2009, from 293 million in 2008. By 2012, the population had jumped to 765 million, and the figure was announced at a popular crab house by Maryland’s former governor, Martin O’Malley, himself.
Unfortunately, the triumph was short-lived — the numbers plunged to 300 million the next year and then hit 297 million in 2014. Some blamed a fish called red drum for eating young crabs; others ascribed the crash to unusual weather patterns, or the loss of eel grass habitat. Although a definitive cause has yet to be identified, one thing is clear: Mathematical models failed to predict it.

For the full commentary, see:
Manil Suri. “Mathematicians and Blue Crabs.” The New York Times, SundayReview Section (Sun., MAY 3, 2015): 4.
(Note: ellipses added.)
(Note: the date of the online version of the commentary is MAY 2, 2015.)

Hamburger Grown in Lab from Cow Stem Cells

(p. D5) A hamburger made from cow muscle grown in a laboratory was fried, served and eaten in London on Monday in an odd demonstration of one view of the future of food.
. . .
The two-year project to make the one burger, plus extra tissue for testing, cost $325,000. On Monday it was revealed that Sergey Brin, one of the founders of Google, paid for the project. Dr. Post said Mr. Brin got involved because “he basically shares the same concerns about the sustainability of meat production and animal welfare.”
The meat was produced using stem cells — basic cells that can turn into tissue-specific cells — from cow shoulder muscle from a slaughterhouse. The cells were multiplied in a nutrient solution and put into small petri dishes, where they became muscle cells and formed tiny strips of muscle fiber. About 20,000 strips were used to make the five-ounce burger, which contained breadcrumbs, salt, and some natural colorings as well.

For the full story, see:
Fountain, Henry. “Frying up a Lab-Grown Hamburger.” The New York Times (Tues., Aug. 6, 2013): D5.
(Note: ellipsis added.)
(Note: the online version of the story has the date Aug. 5, 2013, and has the title “A Lab-Grown Burger Gets a Taste Test.”)

Books that Paved Way to Darwinian Evolution

(p. C6) “Visions of Science” is, as Mr. Secord acknowledges, “a book about books.” We learn more about typeface size, bindery material, print runs and sales figures of the books than about the authors. We would not glean from this account, for example, how intertwined their lives were: They attended the same parties, discussed science together and reviewed one another’s works. Taken together, the books Mr. Secord features tell a fascinating story, and they paved the way to another that is not featured in Mr. Secord’s account but hovers over the others like Davy’s spirit guide.
In “Origin of Species” (1859), Charles Darwin took the central ideas in these books–that there is a connection between the sciences, that the Earth is much older than previously thought, that God created the world to work by uniform natural law, and that He built lawful change into his original creation–and used them to frame his theory of evolution by natural selection in terms his readers could accept. The success of Darwin–and the books that influenced him–is evidenced by the fact that within two decades of its publication most British scientists and much of the public accepted that species evolved.

For the full review, see:
LAURA J. SNYDER. “Reading from the Book of Life; Darwin’s radical ideas were accepted surprisingly quickly by an English public already steeped in science.” The Wall Street Journal (Sat., April 11, 2015): C6.
(Note: ellipses added.)
(Note: the online version of the review has the date April 10, 2015, and has the title “Science Books That Made Modernity; Darwin’s radical ideas were accepted surprisingly quickly by an English public already steeped in science.”)

The book under review is:
Secord, James A. Visions of Science: Books and Readers at the Dawn of the Victorian Age. Chicago: University of Chicago Press, 2015.

Fongoli Chimps, Where Prey Is Scarce, Show “Respect of Ownership”

(p. A10) The Fongoli chimpanzees live in a mix of savanna and woodlands where prey is not as abundant as in rain forests. There are no red colobus monkeys, and although the chimps do hunt young vervet monkeys and baboons, the much smaller bush babies are their main prey.
Dr. Pruetz argues that less food may have prompted both technological and social innovation, resulting in new ways to hunt and new social interactions as well. Humans evolved in a similar environment, and, as she and her colleagues write in Royal Society Open Science, “tool-assisted hunting could have similarly been important for early hominins.”
. . .
By and large, said Dr. Pruetz, the adult males, which could take away a kill, show a “respect of ownership.” Theft rates are only about 5 percent. The chimps she studies also have more mixed-sex social groups than chimp bands in East Africa.
Travis Pickering, an anthropologist at the University of Wisconsin, said that with less food available it seems that the Fongoli chimps, “have to be more inventive” and that “these hunting weapons even the playing field for non-adults and females.”
Early hominins may have been in a similar situation, he said.

For the full story, see:
JAMES GORMAN. “Hunter Chimps Offer New View on Evolution.” The New York Times (Fri., APRIL 15, 2015): A10.
(Note: ellipsis added.)
(Note: the online version of the story has the date APRIL 14, 2015, and has the title “Chimps That Hunt Offer a New View on Evolution.”)

The academic article discussed above is:
Pruetz, Jill D., Paco Bertolani, K. Boyer Ontl, S. Lindshield, M. Shelley, and E. G. Wessling. “New Evidence on the Tool-Assisted Hunting Exhibited by Chimpanzees (Pan Troglodytes Verus) in a Savannah Habitat at Fongoli, Sénégal.” Royal Society Open Science 2, no. 4 (Weds., April 15, 2015), URL: http://rsos.royalsocietypublishing.org/content/2/4/140507.abstract .

Climate Skeptic Vilified by Mainstream Establishment

ChristyJohnClimateSkeptic2015-03-15.jpg“John Christy, a professor of atmospheric science at the University of Alabama, Huntsville, with the weather data he recorded daily while growing up in Fresno, Calif., in the 1960s.” Source of caption and photo: online version of the NYT article quoted and cited below.

(p. A14) “I detest words like ‘contrarian’ and ‘denier,’ ” he said. “I’m a data-driven climate scientist. Every time I hear that phrase, ‘The science is settled,’ I say I can easily demonstrate that that is false, because this is the climate — right here. The science is not settled.”

Dr. Christy was pointing to a chart comparing seven computer projections of global atmospheric temperatures based on measurements taken by satellites and weather balloons. The projections traced a sharp upward slope; the actual measurements, however, ticked up only slightly.
Such charts — there are others, sometimes less dramatic but more or less accepted by the large majority of climate scientists — are the essence of the divide between that group on one side and Dr. Christy and a handful of other respected scientists on the other.
“Almost anyone would say the temperature rise seen over the last 35 years is less than the latest round of models suggests should have happened,” said Carl Mears, the senior research scientist at Remote Sensing Systems, a California firm that analyzes satellite climate readings.
“Where the disagreement comes is that Dr. Christy says the climate models are worthless and that there must be something wrong with the basic model, whereas there are actually a lot of other possibilities,” Dr. Mears said. Among them, he said, are natural variations in the climate and rising trade winds that have helped funnel atmospheric heat into the ocean.
. . .
. . . , Dr. Christy argues that reining in carbon emissions is both futile and unnecessary, and that money is better spent adapting to what he says will be moderately higher temperatures.
. . .
. . . while his work has been widely published, he has often been vilified by his peers.
. . .
He says he worries that his climate stances are affecting his chances of publishing future research and winning grants. The largest of them, a four-year Department of Energy stipend to investigate discrepancies between climate models and real-world data, expires in September.
“There’s a climate establishment,” Dr. Christy said. “And I’m not in it.”

For the full story, see:
MICHAEL WINES. “Though Scorned by Colleagues, a Climate-Change Skeptic Is Unbowed.” The New York Times (Weds., JULY 16, 2014): A14.
(Note: ellipses added.)
(Note: the online version of the story has the date JULY 15, 2014.)

Successful Billionaire Mathematician Would Have Lost Math Contests, But Was Good at Slow Pondering

(p. D1) James H. Simons likes to play against type. He is a billionaire star of mathematics and private investment who often wins praise for his financial gifts to scientific research and programs to get children hooked on math.
But in his Manhattan office, high atop a Fifth Avenue building in the Flatiron district, he’s quick to tell of his career failings.
He was forgetful. He was demoted. He found out the hard way that he was terrible at programming computers. “I’d keep forgetting the notation,” Dr. Simons said. “I couldn’t write programs to save my life.”
After that, he was fired.
His message is clearly aimed at young people: If I can do it, so can you.
. . .
(p. D2) “I wasn’t the fastest guy in the world,” Dr. Simons said of his youthful math enthusiasms. “I wouldn’t have done well in an Olympiad or a math contest. But I like to ponder. And pondering things, just sort of thinking about it and thinking about it, turns out to be a pretty good approach.”

For the full story, see:
WILLIAM J. BROAD. “Seeker, Doer, Giver, Ponderer; A Billionaire Mathematician’s Life of Ferocious Curiosity.” The New York Times (Tues., JULY 8, 2014): D3.
(Note: ellipsis added.)
(Note: the online version of the story has the date JULY 7, 2014.)

“If You Want to Find Something New, Look for Something New!”

(p. D8) Yves Chauvin, who shared the 2005 Nobel Prize in Chemistry for deciphering a “green chemistry” reaction now used to make pharmaceuticals and plastics more efficiently while generating less hazardous waste, died on Tuesday [January 27, 2015] in Tours, France.
. . .
He confessed that he was not a brilliant student, even in chemistry. “I chose chemistry rather by chance,” he wrote, “because I firmly believed (and still do) that you can become passionately involved in your work, whatever it is.”
Mr. Chauvin graduated from the Lyon School of Industrial Chemistry in 1954. Military service and other circumstances prevented him from pursuing a doctoral degree, which he said he regretted. “I had no training in research as such and as a consequence I am in a sense self-taught,” he wrote in his Nobel Prize lecture.
He worked in industry for a few years before quitting, frustrated by an inability to pursue new ideas. “My motto is more, ‘If you want to find something new, look for something new!’ ” Mr. Chauvin wrote. “There is a certain amount of risk in this attitude, as even the slightest failure tends to be resounding, but you are so happy when you succeed that it is worth taking the risk.”
He found the freedom to choose his research when he joined the French Petroleum Institute in 1960, and it led to his breakthrough on metathesis.
“Like all sciences, chemistry is marked by magic moments,” Mr. Chauvin wrote. “For someone fortunate enough to live such a moment, it is an instant of intense emotion: an immense field of investigation suddenly opens up before you.”

For the full obituary, see:
KENNETH CHANG. “Yves Chauvin, Chemist Sharing Nobel Prize, Dies at 84.” The New York Times (Sat., JAN. 31, 2015): D8.
(Note: ellipsis, and bracketed date, added.)
(Note: the online version of the obituary has the date JAN. 30, 2015.)