Science – Page 23 – artdiamondblog.com

We Tend to Ignore Information that Contradicts Our Beliefs

Source of book image: online version of the WSJ review quoted and cited below.

We learn the most when our priors are contradicted. But the dissonance between evidence and beliefs is painful. So we often do not see, or soon forget, evidence that does not fit with our beliefs.
The innovative entrepreneur is often a person who sees and forces herself to remember, the dissonant fact, storing it away to make sense of, or make use of, later. At the start, she may be alone in what she sees and what she remembers. So if we are to benefit from her ability and willingness to bear the pain of dissonance, she must have the freedom to differ, and she must have the financial wherewith-all to support herself until her vision is more widely shared, better understood, and more fruitfully applied.

(p. A13) Beliefs come first; reasons second. That’s the insightful message of “The Believing Brain,” by Michael Shermer, the founder of Skeptic magazine. In the book, he brilliantly lays out what modern cognitive research has to tell us about his subject–namely, that our brains are “belief engines” that naturally “look for and find patterns” and then infuse them with meaning. These meaningful patterns form beliefs that shape our understanding of reality. Our brains tend to seek out information that confirms our beliefs, ignoring information that contradicts them. Mr. Shermer calls this “belief-dependent reality.” The well-worn phrase “seeing is believing” has it backward: Our believing dictates what we’re seeing.
. . .
One of the book’s most enjoyable discussions concerns the politics of belief. Mr. Shermer takes an entertaining look at academic research claiming to prove that conservative beliefs largely result from psychopathologies. He drolly cites survey results showing that 80% of professors in the humanities and social sciences describe themselves as liberals. Could these findings about psychopathological conservative political beliefs possibly be the result of the researchers’ confirmation bias?
As for his own political bias, Mr. Shermer says that he’s “a fiscally conservative civil libertarian.” He is a fan of old-style liberalism, as in liberality of outlook, and cites “The Science of Liberty” author Timothy Ferris’s splendid formulation: “Liberalism and science are methods, not ideologies.” The “scientific solution to the political problem of oppressive governments,” Mr. Shermer says, “is the tried-and-true method of spreading liberal democracy and market capitalism through the open exchange of information, products, and services across porous economic borders.”
But it is science itself that Mr. Shermer most heartily embraces. “The Believing Brain” ends with an engaging history of astronomy that illustrates how the scientific method developed as the only reliable way for us to discover true patterns and true agents at work. Seeing through a telescope, it seems, is believing of the best kind.

For the full review, see:
RONALD BAILEY. “A Trick Of the Mind; Looking for patterns in life and then infusing them with meaning, from alien intervention to federal conspiracy.” The Wall Street Journal (Weds., July 27, 2011): A13.
(Note: ellipsis added.)

Book reviewed:
Shermer, Michael. The Believing Brain: From Ghosts and Gods to Politics and Conspiracies—How We Construct Beliefs and Reinforce Them as Truths. New York: Times Books, 2011.

Lunar Entrepreneurs

(p. A1) Now that the last space shuttle has landed back on Earth, a new generation of space entrepreneurs would like to whip up excitement about the prospect of returning to the Moon.
. . .
(p. A3) “It’s probably the biggest wealth creation opportunity in modern history,” said Barney Pell, a former NASA computer scientist turned entrepreneur and now a co-founder of Moon Express. While Moon Express might initially make money by sending small payloads, the big fortune would come from bringing back platinum and other rare metals, Dr. Pell said.
“Long term, the market is massive, no doubt,” he said. “This is not a question of if. It’s a question of who and when. We hope it’s us and soon.”
Like the aviation prizes that jump-started airplane technology a century ago, the Google Lunar X Prize is meant to rally technologists and entrepreneurs. It is administered by the X Prize Foundation, which handed out $10 million in 2004 to the first private team to build a spacecraft that could carry people 60 miles above the Earth’s surface. (The winner, SpaceShipOne, was built by the aerospace designer Burt Rutan with backing from Paul Allen, the software magnate.)

For the full story, see:
KENNETH CHANG. “In a Private Race to the Moon, Flights of Fancy Are in the Air.” The New York Times (Fri., July 22, 2011): A1 & A3.
(Note: the online version of the story is dated July 21, 2011 and has the title “Race to the Moon Heats Up for Private Firms.”)

John Crandon Proved Scurvy Caused by Lack of Vitamin C

(p. 167) . . . , in 1939 a Harvard Medical School surgeon named John Crandon decided to settle matters once and for all by the age-old method of withholding Vitamin C from his diet for as long as it took to make himself really ill. It took a surprisingly long time. For the first eighteen weeks, his only symptom was extreme fatigue. (Remarkably, he continued to operate on patients throughout this period.) But in the nineteenth week he took an abrupt turn for the worse – so much so that he would almost certainly have died had he not been under close medical supervision. He was injected with 1,000 milligrams of Vitamin C and was restored to life (p. 168) almost at once. Interestingly, he had never acquired the one set of symptoms that everyone associates with scurvy: the falling out of teeth and bleeding of gums.

Source:
Bryson, Bill. At Home: A Short History of Private Life. New York: Doubleday, 2010.
(Note: ellipsis added.)

Obstacles to Curing Scurvy: A Deadly Experiment and Putting Theory Before Evidence

(p. 165) What was needed was some kind of distilled essence – an antiscorbutic, as the medical men termed it – that would be effective against scurvy but portable too. In the 1760s, a Scottish doctor named William Stark, evidently encouraged by Benjamin Franklin, conducted a series of patently foolhardy experiments in which he tried (p. 166) to identify the active agent by, somewhat bizarrely, depriving himself of it. For weeks he lived on only the most basic of foods – bread and water chiefly – to see what would happen. What happened was that in just over six months he killed himself, from scurvy, without coming to any helpful conclusions at all.
In roughly the same period, James Lind, a naval surgeon, conducted a more scientifically rigorous (and personally less risky) experiment by finding twelve sailors who had scurvy already, dividing them into pairs, and giving each pair a different putative elixir – vinegar to one, garlic and mustard to another, oranges and lemons to a third, and so on. Five of the groups showed no improvement, but the pair given oranges and lemons made a swift and total recovery. Amazingly, Lind decided to ignore the significance of the result and doggedly stuck with his personal belief that scurvy was caused by incompletely digested food building up toxins within the body.

Source:
Bryson, Bill. At Home: A Short History of Private Life. New York: Doubleday, 2010.

Drug from David Sinclair’s Sirtris Start-Up Lengthens Life of Obese Mice

“An obese mouse given the drug SRT-1720, center, and one not given the drug, right.” Source of caption and photo: online version of the NYT article quoted and cited below.

(p. A1) Sustaining the flickering hope that human aging might somehow be decelerated, researchers have found they can substantially extend the average life span of obese mice with a specially designed drug.

The drug, SRT-1720, protects the mice from the usual diseases of obesity by reducing the amount of fat in the liver and increasing sensitivity to insulin. These and other positive health effects enable the obese mice to live 44 percent longer, on average, than obese mice that did not receive the drug, according to a team of researchers led by Rafael de Cabo, a gerontologist at the National Institute on Aging.
Drugs closely related to SRT-1720 are now undergoing clinical trials in humans.
The findings “demonstrate for the first time the feasibility of designing novel molecules that are safe and effective in promoting longevity and preventing multiple age-related diseases in mammals,” Dr. de Cabo and colleagues write in Thursday’s issue of the new journal Scientific Reports. Their conclusion supports claims that had been thrown in doubt by an earlier study that was critical of SRT-1720.
A drug that makes it cost-free to be obese may seem more a moral hazard than an incentive to good health. But the rationale behind the research is somewhat different: the researchers are trying to capture the benefits that allow mice on very low-calorie diets to live longer. It just so happens that such benefits are much easier to demonstrate in mice under physiological stress like obesity than in normal mice.
. . .
. . . , a small pharmaceutical concern in Cambridge, Mass., designed SRT-1720 and a set of similar drugs to mimic resveratrol — the trace ingredient of red wine that is thought to activate protective proteins called sirtuins.
The sirtuins help bring about the 30 percent extension of life span enjoyed by mice and rats that are kept on very low-calorie diets.

For the full story, see:
NICHOLAS WADE. “Longer Lives for Obese Mice, With Hope for Humans of All Sizes.” The New York Times (Fri., August 19, 2011): A1 & A3.
(Note: ellipses added.)
(Note: the online version of the story was dated August 18, 2011.)

“A Brilliant and Exhilarating and Profoundly Eccentric Book”

“David Deutsch.” Source of caption and photo: online version of the NYT review quoted and cited below.

(p. 16) David Deutsch’s “Beginning of Infinity” is a brilliant and exhilarating and profoundly eccentric book. It’s about everything: art, science, philosophy, history, politics, evil, death, the future, infinity, bugs, thumbs, what have you. And the business of giving it anything like the attention it deserves, in the small space allotted here, is out of the question. But I will do what I can.
. . .
The thought to which Deutsch’s conversation most often returns is that the European Enlightenment of the 17th and 18th centuries, or something like it, may turn out to have been the pivotal event not merely of the history of the West, or of human beings, or of the earth, but (literally, physically) of the universe as a whole.
. . .
(p. 17) Deutsch’s enthusiasm for the scientific and technological transformation of the totality of existence naturally brings with it a radical impatience with the pieties of environmentalism, and cultural relativism, and even procedural democracy — and this is sometimes exhilarating and sometimes creepy. He attacks these pieties, with spectacular clarity and intelligence, as small-minded and cowardly and boring. The metaphor of the earth as a spaceship or life-support system, he writes, “is quite perverse. . . . To the extent that we are on a ‘spaceship,’ we have never merely been its passengers, nor (as is often said) its stewards, nor even its maintenance crew: we are its designers and builders. Before the designs created by humans, it was not a vehicle, but only a heap of dangerous raw materials.” But it’s hard to get to the end of this book without feeling that Deutsch is too little moved by actual contemporary human suffering. What moves him is the grand Darwinian competition among ideas. What he adores, what he is convinced contains the salvation of the world, is, in every sense of the word, The Market.

For the full review, see:
DAVID ALBERT. “Explaining it All: David Deutsch Offers Views on Everything from Subatomic Particles to the Shaping of the Universe Itself.” The New York Times Book Review (Sun., August 14, 2011): 16-17.
(Note: ellipses between paragraphs added; ellipsis in Deutsch quote in original.)
(Note: the online version of the review is dated August 12, 2011 and has the title “Explaining it All: How We Became the Center of the Universe.”)

Book under review:
Deutsch, David. The Beginning of Infinity: Explanations That Transform the World. New York: Viking Adult, 2011.

A Case for Epistemic and Technological Optimism

Source of book image: http://us.penguingroup.com/static/covers/all/5/5/9780670022755H.jpg

Horgan is well-known for writing a pessimistic book about the future of science. For him to write such a positive review of a book that reaches the opposite conclusion, is impressive (both about him and the book he is reviewing).
From Horgan’s review and the reviews on Amazon as of 8/7/11, I view the Deutsch book as potentially important and profound. (I will write more when I have read it.)

(p. 17) . . . Mr. Deutsch knocks my 1996 book, “The End of Science,” for proposing that the glory days of science–especially pure science, the effort to map out and understand reality–may be over. Mr. Deutsch equates my thesis with “dogmatism, stagnation and tyranny,” all of which, for the record, I oppose. But he makes the case for infinite progress with such passion, imagination and quirky brilliance that I couldn’t help enjoying his argument. More often than not I found myself agreeing with him–or at least hoping that he is right.
. . .
If we acknowledge our imperfections, Mr. Deutsch observes, then, paradoxically, there is no problem that we cannot tackle. Death, for instance. Or the apparent incompatibility between the two pillars of modern physics, quantum theory and general relativity. Or global warming, which Mr. Deutsch believes we can overcome through innovation rather than drastic cutbacks in consumption. He gores the sacred cow of “sustainability”: Societies are healthiest, he declares, not when they achieve equilibrium but when they are rapidly evolving.

For the full review, see:
JOHN HORGAN. “BOOKSHELF; To Err Is Progress; How to foster the growth of scientific knowledge: accept that it is limited no matter how definitive it may seem.” The Wall Street Journal (Weds., JULY 20, 2011): A17.
(Note: ellipses added.)

Source information on book under review:
Deutsch, David. The Beginning of Infinity: Explanations That Transform the World. New York: Viking Adult, 2011.

Cow Burps and Farts Cause 28% of Methane Release “Due to Human Activity”

(p. 6A) LOS ANGELES — Scientists have isolated a bacterium from the gut of Australian Tammar wallabies that allows the animals to consume and digest grasses, leaves and other plant material without producing copious amounts of methane, as cattle do.
The microbe was discovered through a process described in a report published online recently by the journal Science.
Ultimately, the microbe might be put to use to reduce the carbon footprint of cows and other ruminants, said report co-author Mark Morrison, a microbial biologist in St. Lucia, Queensland.
. . .
The methane-rich burps and flatulence of cattle have been blamed for 28 percent of that greenhouse gas’s global emissions due to human activity. Like other cud-chewing mammals, they produce methane as their systems work to break down and ferment the plant matter they eat.

For the full story, see:
THE LOS ANGELES TIMES. “Wallaby microbe may one day help cut cows’ methane footprint.” Omaha World-Herald (Monday, July 4, 2011): 6A.
(Note: ellipsis added.)

“Progress Depended on the Empirical Habit of Thought”

In the passage below from 1984 Orwell presents an underground rebel’s account of why the authoritarian socialist dystopia cannot advance in science and technology.

(p. 155) The world of today is a bare, hungry, dilapidated place compared with the world that existed before 1914, and still more so if compared with the imaginary future to which the people of that period looked forward. In the early twentieth century, the vision of a future society unbelievably rich, leisured, orderly, and efficient–a glittering (p. 156) antiseptic world of glass and steel and snow-white concrete–was part of the consciousness of nearly every literate person. Science and technology were developing at a prodigious speed, and it seemed natural to assume that they would go on developing. This failed to happen, partly because of the impoverishment caused by a long series of wars and revolutions, partly because scientific and technical progress depended on the empirical habit of thought, which could not survive in a strictly regimented society.

Source:
Orwell, George. Nineteen Eighty-Four. New York: The New American Library, 1961 [1949].

By Canadian law, 1984 is no longer under copyright. The text has been posted on the following Canadian web site: http://wikilivres.info/wiki/Nineteen_Eighty-Four

“When There Is a Massive Release of Methane, the Ocean Can Compensate”

“Dr. John Kessler, lead author of the study, examining a water sample.” Source of caption and photo: online version of the WSJ article quoted and cited below.

(p. A3) Bacteria made quick work of the tons of methane that billowed into the Gulf of Mexico along with oil from the Deepwater Horizon blowout, clearing the natural gas from the waterway within months of its release, researchers reported Friday.

The federally funded field study, published online in the journal Science, offers peer-reviewed evidence that naturally occurring microbes in the Gulf devoured significant amounts of toxic chemicals in natural gas and oil spewing from the seafloor, which researchers had thought would persist in the region’s water chemistry for years.
“Within a matter of months, the bacteria completely removed that methane,”said microbiologist David Valentine at the University of California at Santa Barbara. “The bacteria kicked on more effectively than we expected,” he said.
. . .
“We were shocked,” said chemical oceanographer John Kessler at Texas A&M, who was the lead author of the Science study. “We thought the methane would be around for years.”
. . .
“They showed that, even when there is a massive release of methane, the ocean can compensate,” said federal microbiologist Terry Hazen at the Lawrence Livermore National Laboratory, who has long championed the use of methane-oxidizing microbes to biodegrade oil spills.

For the full story, see:
ROBERT LEE HOTZ. “Microbes Mopped Up After Spill; Bacteria Swiftly Devoured Methane Unleashed Into the Gulf of Mexico, Study Says.” The Wall Street Journal (Fri., January 7, 2011): A3.
(Note: ellipses added.)

The Science article mentioned above, is:
Kessler, John D., David L. Valentine, Molly C. Redmond, Mengran Du, Eric W. Chan, Stephanie D. Mendes, Erik W. Quiroz, Christie J. Villanueva, Stephani S. Shusta, Lindsay M. Werra, Shari A. Yvon-Lewis, and Thomas C. Weber. “A Persistent Oxygen Anomaly Reveals the Fate of Spilled Methane in the Deep Gulf of Mexico.” Science (Jan. 6, 2011).

Source of graph: online version of the WSJ article quoted and cited above.