Category: Entrepreneurship

The “Miracle Machines” of Farming

(p. 75) Nobody had washing machines, vacuum cleaners, or incandescent light bulbs. But the farmers did have their miracle machines. In fifteen years, the Lucas family had gone from a walking plow pulled along behind a mule, to a riding plow, in which horses carried the blade through the soil, to a fine-tuned internal combustion plow.
“Machinery is the new Messiah,” said Henry Ford, and though that sounded blasphemous to a devout sodbuster, there was something to it. Every ten seconds a new car came off Ford’s factory line, and some of them were now parked next to dugouts in No Man’s Land.

Source:
Egan, Timothy. The Worst Hard Time: The Untold Story of Those Who Survived the Great American Dust Bowl. Boston: Houghton Mifflin, 2006.

“Valuable Things Should Be Paid For . . . Music Should Not Be Free”

(p. R10) Music is art, and art is important and rare. Important, rare things are valuable. Valuable things should be paid for. It’s my opinion that music should not be free, and my prediction is that individual artists and their labels will someday decide what an album’s price point is. I hope they don’t underestimate themselves or undervalue their art.

For the full commentary, see:
Swift, Taylor. “WSJ 125 (A Special Report): Music — it’s Too Soon to Write Off the Album: Yes, Musicians Aren’t Selling as Many of them; but Taylor Swift Argues that the Best Artists Will always Find Ways to Break through to the Audience.” Wall Street Journal (Tues., July 8, 2014): R10.
(Note: the online version of the commentary has the date July 7, 2014, and has the title “For Taylor Swift, the Future of Music Is a Love Story.”)

More Than 200,000 Volunteer to Die if They Can Be on First (One Way) Trip to Mars

(p. D2) When Seth Shostak, an astronomer who scans the cosmos for signs of extraterrestrial intelligence, asks middle school students how many of them want to go to Mars, all hands shoot up. When he asks how many would rather design robots that go to Mars, most hands drop back to their desks.
And when he asks general audiences how many would go to Mars even if it meant dying a few weeks after arriving, he invariably finds volunteers in the crowd. “I kid you not,” said Dr. Shostak, the director of the Center for SETI Research. “People are willing to risk everything just to see Mars, to walk on the surface of our little ruddy buddy.”
. . .
There is a catch, they say. Where NASA-style flight plans are designed on the Apollo moonshot model of round-trip tickets, the “one” in Mars One means, starkly, one way. To make the project feasible and affordable, the founders say, there can be no coming back to Earth. Would-be Mars pilgrims must count on living, and dying, some 140 million miles from the splendid blue marble that all humans before them called home.
Nevertheless, enthusiasm for the Mars One scheme has been of middle-school proportions. Last year, the outfit announced that it was seeking potential colonists and that anybody over age 18 could apply, advanced degrees or no. Among the few stipulations: Candidates must be between 5-foot-2 and 6-foot-2, have a ready sense of humor and be “Olympians of tolerance.” More than 200,000 people from dozens of countries applied. Mars One managers have since whittled the pool to some 660 semifinalists.

For the full story, see:
Angier, Natalie. “Basics; a One-Way Trip to Mars? Many Would Sign Up.” The New York Times (Tues., Dec. 9, 2014): D2.
(Note: ellipsis added.)
(Note: the online version of the story has the date Dec. 8, 2014.)

“You Don’t Reach Serendip by Plotting a Course for It”

(p. 320) As John Barth wrote in The Last Voyage of Somebody the Sailor, “You don’t reach Serendip by plotting a course for it. You have to set out in good faith for elsewhere and lose your bearings serendipitously.”28 The challenge for educational institutions, government policy, research centers, funding agencies, and, by extension, all modern medicine, will be how to encourage scientists to lose their bearings creatively. What they discover may just save our lives!

Source:
Meyers, Morton A. Happy Accidents: Serendipity in Modern Medical Breakthroughs. New York: Arcade Publishing, 2007.
(Note: italics in original.)

As with Airplanes, Lives Must Be Risked to Achieve Routine Safety in Spaceships

(p. A21) SEATTLE — ONE clear winter day in 1909, in Hampshire, England, a young man named Geoffrey de Havilland took off in a twin-propeller motorized flying machine of his own design, built of wood, piano wire and stiff linen hand-stitched by his wife. The launch was flawless, and soon he had an exhilarating sensation of climbing almost straight upward toward the brilliant blue sky. But he soon realized he was in terrible trouble.
The angle of ascent was unsustainable, and moments later de Havilland’s experimental plane crashed, breaking apart into a tangled mass of shards, splinters and torn fabric, lethal detritus that could easily have killed him even if the impact of smashing into the ground did not. Somehow, he survived and Sir Geoffrey — he was ultimately knighted as one of the world’s great aviation pioneers — went on to build an astonishing array of military and civilian aircraft, including the world’s first jet airliner, the de Havilland Comet.
I thought immediately of de Havilland on Friday when I heard that Virgin Galactic’s SpaceShipTwo, a rocket-powered vehicle designed to take well-heeled tourists to the edge of space, had crashed on a flight over the Mojave Desert, killing one test pilot and seriously injuring the other.
. . .
Certainly the Wright brothers and others like de Havilland were involved in what we now view as an epic quest, but many experts of the day were certain that flight, however interesting, was destined to be not much more than a rich man’s hobby with no practical value.
“The public has greatly over-estimated the possibilities of the aeroplane, imagining that in another generation they will be able to fly over to London in a day,” said a Harvard expert in 1908. “This is manifestly impossible.” Two other professors patiently explained that while laymen might think that “because a machine will carry two people another may be constructed that will carry a dozen,” in fact “those who make this contention do not understand the theory of weight sustentation in the air.”
. . .
There will be tragedies like the crash of SpaceShipTwo and nonlethal setbacks such as the fiery explosion, also last week, of a remote-controlled rocket intended for a resupply mission to the International Space Station. There will be debates about how to improve regulation without stifling innovation. Some will say private industry can’t do the job — though it’s not as if the NASA-sponsored Apollo or space shuttle missions went off without a hitch (far from it, sadly).
But at the heart of the enterprise there will always be obsessives like Sir Geoffrey, who forged ahead with his life’s work of building airplanes despite his own crash and, incredibly, the deaths of two of his three sons while piloting de Havilland aircraft, one in an attempt to break the sound barrier. Getting to routine safety aloft claimed many lives along the way, and a hundred years from now people will agree that in that regard, at least, spaceships are no different from airplanes.

For the full commentary, see:
SAM HOWE VERHOVEK. “Not a Flight of Fancy.” The New York Times (Tues., NOV. 4, 2014): A21.
(Note: ellipses added.)
(Note: the online version of the commentary has the date NOV. 3, 2014.)

Outsiders Persevere to Pursue Breakthroughs

(p. 315) Despite all the examples given, mainstream medical research stubbornly continues to assume that new drugs and other advances will follow exclusively from a predetermined research path. Many, in fact, will. Others, if history is any indication, will not. They will come not from a committee or a research team but from an individual, a maverick who views a problem with fresh eyes. Serendipity will strike and be seized upon by a well-trained scientist or clinician who also dares to rely upon intuition, imagination, and creativity. Unbound by traditional theory, willing to suspend the usual set of beliefs, unconstrained by the requirement to obtain approval or funding for his or her pursuits, this outsider will persevere and lead the way to a dazzling breakthrough. Eventually, once the breakthrough becomes part of accepted medical wisdom, the insiders will pretend that the outsider was one of them all along.

Source:
Meyers, Morton A. Happy Accidents: Serendipity in Modern Medical Breakthroughs. New York: Arcade Publishing, 2007.

Successful Discoverers “Follow the Evidence Wherever It Leads”

(p. 314) Why are particular people able to seize on such opportunities and say, “I’ve stumbled upon a solution. What’s the problem?” Typically, such people are not constrained by an overly focused or dogmatic mindset. In contrast, those with a firmly held set of preconceptions are less likely to be distracted by an unexpected or contradictory observation, and yet it is exactly such things that lead to the blessing of serendipitous discovery.
Serendipitous discoverers have certain traits in common. They have a passionate intensity. They insist on trying to see beyond their own and others’ expectations and resist any pressure that would close off investigation. Successful medical discoverers let nothing stand in their way. They break through, sidestep, or ignore any obstacle or objection to their chosen course, which is simply to follow the evidence wherever it leads. They have no patience with dogma of any kind.
The only things successful discoverers do not dismiss out of hand are contradictory–and perhaps serendipitously valuable–facts. They painstakingly examine every aspect of uncomfortable facts until they understand how they fit with other facts. Far from being cavalier about method, serendipitous discoverers subject their evidence and suppositions to the most rigorous methods they can find. They do not run from uncertainty, but see it as the raw material from which new scientific and medical certainties can be wrought.

Source:
Meyers, Morton A. Happy Accidents: Serendipity in Modern Medical Breakthroughs. New York: Arcade Publishing, 2007.

Resilience of Ordinary People Matters Most in Early Stages of Crisis

(p. A11) Throughout “The Resilience Dividend,” Ms. Rodin pays particular attention to the influence that ordinary people can have in a crisis, especially in the early stages, when it may not be clear what has happened and the professionals haven’t had time to put a plan into place. In the minutes after Boston Marathon bombing last year, citizens rushed forward to help the injured. In New York City on 9/11, hundreds of privately owned boats carried thousands of stranded commuters off the island of Manhattan and across the Hudson River to New Jersey.

For the full review, see:
MELANIE KIRKPATRICK. “BOOKSHELF; Never Waste a Crisis; How was the city of Medellín transformed from the murder capital of South America into a thriving urban center? Escalators.” The Wall Street Journal (Fri., Nov. 21, 2014): A11.
(Note: the online version of the review has the date Nov. 20, 2014.)

The book being reviewed is:
Rodin, Judith. The Resilience Dividend: Being Strong in a World Where Things Go Wrong. New York: PublicAffairs, 2014.

Bezos Devices Aim to Create a Virtuous Cycle ‘Flywheel’

(p. B1) Amazon now makes four different kinds of devices. There are dedicated e-readers, multipurpose tablets and, starting this year, a TV streaming device and a smartphone, the Fire Phone. Just this week, Amazon introduced another streaming machine, the Fire TV Stick, a $39 gadget that is the size of a USB stick and promises to turn your television into an Amazon-powered video service.
. . .
(p. B9) What is Amazon’s endgame with all these devices? Mr. Bezos has always said that his mission, with hardware, is to delight users with devices that are priced fairly. The devices also contribute to Mr. Bezos’s famous “flywheel,” the virtuous cycle by which greater customer satisfaction leads to more sellers in his store, which leads to more products, greater efficiencies, lower prices and, in turn, more customers.
“Everything is about getting that flywheel spinning, and it isn’t necessarily about building a big and successful tablet business of their own,” said Benedict Evans, an analyst who works at the investment firm Andreessen Horowitz and has studied Amazon closely. “Whether they actually drive meaningful commerce isn’t entirely clear, but Amazon is rigorously focused on data, so if they’re doing it, you can trust that there must be data that justifies it.”
And if this year’s devices don’t take off, you can bet that Mr. Bezos will try a slightly different tack next year.

For the full commentary, see:
Farhad Manjoo. “STATE OF THE ART; Amazon’s Grand Design for Devices.” The New York Times (Thurs., OCT. 30, 2014): B1 & B9.
(Note: ellipsis added.)
(Note: the online version of the commentary has the date OCT. 29, 2014, and has the title “STATE OF THE ART; Amazon’s Grand Design in Devices.”)

Bezos’s enthusiasm for Jim Collins’s “flywheel” idea is discussed in:
Stone, Brad. The Everything Store: Jeff Bezos and the Age of Amazon. New York: Little, Brown and Company, 2013.

While Looking for Spotted Fever, He Found the Cause of Lyme Disease

(p. A25) Willy Burgdorfer, a medical entomologist who in 1982 identified the cause of what had been a mysterious affliction, Lyme disease, died on Monday [November 17, 2014] at a hospital in Hamilton, Mont. He was 89.
. . .
In the early 1980s, Dr. Burgdorfer was analyzing deer ticks from Long Island that were suspected to have caused spotted fever when he stumbled on something unexpected under his microscope: spirochetes, disease-causing bacteria shaped like corkscrews. They were located in only one section of the ticks, the so-called midguts. He had studied spirochetes in graduate school.
“Once my eyes focused on these long, snakelike organisms, I recognized what I had seen a million times before: spirochetes,” he said in a 2001 oral history for the National Institutes of Health, which include the National Institute of Allergy and Infectious Diseases.
He had not been working on Lyme disease, but he had spoken with the doctor who helped discover it, Dr. Allen Steere of Yale. After he saw the spirochetes in the Long Island ticks, he quickly realized that the bacteria might also be in the deer ticks believed to be playing a role in Lyme disease in Connecticut and elsewhere, including Long Island.

For the full obituary, see:
WILLIAM YARDLEY. “Willy Burgdorfer, Who Found Bacteria That Cause Lyme Disease, Is Dead at 89.” The New York Times (Thurs., NOV. 20, 2014): A25.
(Note: ellipsis, and bracketed date, added.)
(Note: the online version of the obituary has the date NOV. 19, 2014.)