“Peer Review Institutionalizes Dogmatism by Promoting Orthodoxy”

(p. 305) Peer review institutionalizes dogmatism by promoting orthodoxy. Reviewers prefer applications that mesh with their own perspective on how an issue should be conceptualized, and they favor individuals whom they know or whose reputations have already been established, making it harder for new people to break into the system.6 Indeed, the basic process of peer review demands conformity of thinking and disdains a maverick’s approach. “We can hardly expect a committee,” said the biologist and historian of science, Garrett Hardin, “to acquiesce in the dethronement of tradition. Only an individual can do that.”7 Young investigators get the message loud and clear: Do not challenge existing beliefs and practices.
So enmeshed in the conventional wisdoms of the day, so-called “peers” have again and again failed to appreciate major breakthroughs even when they were staring them in the face. This reality is evidenced by the fact that so many pioneering researchers were inappropriately scheduled to present their findings at undesirable times when few people were in the audience to hear about them.

Source:
Meyers, Morton A. Happy Accidents: Serendipity in Modern Medical Breakthroughs. New York: Arcade Publishing, 2007.

French Entrepreneurs Protest Government Crushing Them with Taxes and Regulations

FrenchBossesProtest2014-12-26.jpg “Protesting business owners in Paris brandished locks and chains to signify the constraints they said the government imposed on French businesses.” Source of caption and photo: online version of the NYT article quoted and cited below.

(p. B3) PARIS — They jammed the boulevards, blowing whistles, tossing firecrackers, wearing locks and chains around their necks, and shouting into megaphones: “Enough is enough!”

In France, where protest marches are a well-practiced tradition, it is usually workers who take to the streets. But in a twist on Monday, thousands of French bosses demonstrated in Paris and Toulouse, the opening act in a weeklong revolt against government regulations and taxes that they say are straitjacketing companies, discouraging hiring and choking the economy.
“We feel like we’re being taken hostage,” said Laurence Manabre, owner of a home-maintenance business that has 28 workers — but could employ many more, she said, if not for onerous government-imposed labor rules.
Ms. Manabre marched with the throng toward the Finance Ministry, brandishing a bronze lock, a symbol that hundreds of other bosses wore to signify the constraints they said the Socialist government imposed on French businesses. “Between regulations, taxes, new laws, and razor-thin margins,” she said, “we’re being crushed little by little.”
. . .
. . . there are . . . entrenched parts of the French labor code, which employers say make it a difficult, lengthy process to lay off employees, and make bosses reluctant to take on new workers, especially with permanent contracts.
“France has high unemployment,” Ms. Manabre said. “But the French labor code is incomprehensible, and it just keeps getting more complex. How can I possibly hire more people?”
. . .
Mr. Roland has 35 employees, and his son is supposed to take over the business when he retires. But now his son is thinking of leaving the country, Mr. Roland said, because “France doesn’t seem to have a future, and the conditions for entrepreneurs are difficult.”
Mr. Roland said he did not plan to hire more workers, out of concern that coming regulations would menace his already-thin profit margins.

For the full story, see:
LIZ ALDERMAN. “In Twist on French Tradition, Bosses Take to Streets in Protest.” The New York Times (Tues., DEC. 2, 2014): B3.
(Note: ellipses added.)
(Note: the online version of the story has the date DEC. 1, 2014,)

With Targeted Research, Scientists Not Allowed to Pursue Serendipitous Discoveries

(p. 303) When scientists were allowed to pursue whatever they found, serendipitous discovery flourished.
Today, targeted research is pretty much all there is. Yet, as Richard Feynman put it in his typical rough-hewn but insightful manner, giving more money “just increases the number of guys following the comet head.”2 Money doesn’t foster new ideas, ideas that drive science; it only fosters applications of old ideas, most often enabling improvements but not discoveries.

Source:
Meyers, Morton A. Happy Accidents: Serendipity in Modern Medical Breakthroughs. New York: Arcade Publishing, 2007.

Pentagon Bureaucracy “Hindered Progress” on Drones

(p. A13) Compared with, say, a B-2 Bomber, drones are simple things. An empty B-2 weighs 158,000 pounds. The largest version of the Predator–the unmanned aerial vehicle now playing a critical role in every theater where the American military is engaged–weighs just under 5,000. Yet these small aircraft are revolutionizing warfare. Given the simplicity of drones, why did it take so long to put them into operation?
. . .
The most alarming take-away from Mr. Whittle’s history is the persistent opposition of officials in the Pentagon who, for bureaucratic reasons, hindered progress at every step of the way.
A case in point: Two months after 9/11, the Predator was employed to incinerate one of al Qaeda’s senior operatives, Mohammed Atef. The same blast also incinerated–metaphorically–a study released two weeks earlier by the Pentagon’s office of operational testing and evaluation. The study had declared Predator “not operationally effective or suitable” for combat. If one seeks to understand why the drone revolution was late in coming–too late to help avert 9/11–the hidebound mentality behind that Pentagon document is one place to start.

For the full review, see:
Gabriel Schoenfeld. “BOOKSHELF; Building Birds of Prey; Red tape at the Pentagon prevented the development of a drone that could have helped avert the attacks of Sept. 11, 2001.” The Wall Street Journal (Tues., Sept. 16, 2014): A13.
(Note: ellipsis added.)
(Note: the online version of the review has the date Sept. 15, 2014, and has the title “BOOKSHELF; Book Review: ‘Predator’ by Richard Whittle; Red tape at the Pentagon prevented the development of a drone that could have helped avert the attacks of Sept. 11, 2001.”)

The book under review is:
Whittle, Richard. Predator: The Secret Origins of the Drone Revolution. New York, NY: Henry Holt and Co., 2014.

Government Funding Rewards Conformity

(p. 302) Inherent in the system is a mindset of conformity: one will tend to submit only proposals that are likely to be approved, which is to say, those that conform to the beliefs of most members on the committee of experts. Because of the intense competition for limited money, investigators are reluctant to submit novel or maverick proposals. Needless to say, this environment stifles the spirit of innovation. Taking risks, pioneering new paths, thwarting conventional wisdom–the very things one associates with the wild-eyed, wild-haired scientists of the past–don’t much enter into the picture nowadays.

Source:
Meyers, Morton A. Happy Accidents: Serendipity in Modern Medical Breakthroughs. New York: Arcade Publishing, 2007.

Somewhere in a Garage Is the Next Google

(p. B6) . . . Monday [Oct. 13, 2014] Eric Schmidt, Google’s executive chairman used a speech in Berlin to talk about Amazon’s success in search, how Facebook crushed Google on social networking and his conviction that somewhere in the world there is a garage-based company that will take out Google.
. . .
Here are some excerpts from Mr. Schmidt’s speech:
. . .
THE NEXT GOOGLE: “But more important, someone, somewhere in a garage is gunning for us. I know, because not long ago we were in that garage. … The next Google won’t do what Google does, just as Google didn’t do what AOL did.”

For the full story, see:
CONOR DOUGHERTY. “Google Chairman on Competition.” The New York Times (Mon., OCT. 20, 2014): B6.
(Note: bolded words, and last ellipsis, in original; other ellipses, and bracketed date, added.)
(Note: the online version of the story has the date OCT. 14, 2014, and has the title “Google Executive Chairman: Amazon Is a Lovely Place to Shop and Search.” There are minor differences between the print and online versions. In the passages quoted above, where the two differ, I follow the print version.)

FAA Requires Drones to Carry Onboard Manuals

(p. B1) BERLIN–In four years, Service-drone.de GmbH has emerged as a promising player here in the rapidly expanding commercial-drone industry. The 20-employee startup has sold more than 400 unmanned aircraft to private-sector companies and now is pitching its fourth-generation device.
Over the same period, Seattle-based Applewhite Aero has struggled to get permission from the Federal Aviation Administration just to fly its drones, which are designed for crop monitoring. The company, founded the same year as Service-drone, has test-flown only one of its four aircraft, and is now moving some operations to Canada, where getting flight clearance is easier.
“We had to petition the FAA to not carry the aircraft manual onboard,” said Applewhite founder Paul Applewhite. “I mean, who’s supposed to read it?” Mr. Applewhite, like many of his U.S. peers, fears the drone industry “is moving past the U.S., and we’re just getting left behind.”

For the full story, see:
JACK NICAS. “U.S. Rules Clips Drone Makers’ Wings.” The Wall Street Journal (Mon., Oct. 6, 2014): B1 & B4.
(Note: the online version of the story has the date Oct. 5, 2014, and has the title “Regulation Clips Wings of U.S. Drone Makers.”)

Government Funding Not Conducive to Serendipity

(p. 301) Even in the early twentieth century, the climate was more conducive to serendipitous discovery. In the United States, for example, scientific research was funded by private foundations, notably the Rockefeller Institute for Medical Research in New York (established 1901) and the Rockefeller Foundation (1913). The Rockefeller Institute modeled itself on prestigious European organizations such as the Pasteur Institute in France and the Koch Institute in Germany, recruiting the world’s best scientists and providing them with comfortable stipends, well-equipped laboratories, and freedom from teaching obligations and university politics, so that they could devote their energies to research. The Rockefeller Foundation, which was the most expansive supporter of basic research, especially in biology, between the two world wars, relied on successful programs to seek promising scientists to identify and accelerate burgeoning fields of interest. In Britain, too, the Medical Research Council believed in “picking the man, not the project,” and nurturing successful results with progressive grants.
After World War II, everything about scientific research changed. The U.S. government–which previously had had little to do with funding research except for some agricultural projects–took on a major role. The National Institutes of Health (NIH) grew out of feeble beginnings in 1930 but became foremost among the granting agencies in the early 1940s at around the time they moved to Bethesda, Maryland. The government then established the National Science Foundation (NSF) in 1950 to promote progress in science and engineering. Research in the United States became centralized and therefore suffused with bureaucracy. The lone scientist working independently was now a rarity. Research came to be characterized by large teams drawing upon multiple scientific disciplines and using highly technical methods in an environment that promoted the not-very-creative phenomenon known as “groupthink.” Under this new regime, the competition (p. 302) among researchers for grant approvals fostered a kind of conformity with existing dogma. As the bureaucracy of granting agencies expanded, planning and justification became the order of the day, thwarting the climate in which imaginative thought and creative ideas flourish.

Source:
Meyers, Morton A. Happy Accidents: Serendipity in Modern Medical Breakthroughs. New York: Arcade Publishing, 2007.

“Bad Ideas Die Hard, Especially Those that Flatter Our Vanity”

(p. C5) Mütter was one of the first plastic surgeons in America.
. . .
Mütter was also a pioneer of burn surgery.
. . .
Every hero needs a good antagonist and Mütter had a great one, a professor and blowhard named Charles D. Meigs who was as contrary as a Missouri mule. Meigs was a highly regarded obstetrician and one of Mütter’s colleagues at Jefferson. He rejected Mütter’s namby-pamby notions by reflex. Anesthesia? Pshaw! Men and women are put on earth to suffer. Handwashing? Humbug! The very idea that physicians could spread disease was preposterous. As Meigs wrote, “a gentleman’s hands are clean.” Unfortunately, bad ideas die hard, especially those that flatter our vanity. The fight to make medicine as humane as possible continues long after Mütter’s premature death from tuberculosis in 1859.

For the full review, see:
JOHN ROSS. “The Doctor Will See You Now.” The Wall Street Journal (Sat., Aug. 30, 2014): C5.
(Note: ellipses added.)
(Note: the online version of the review has the date Aug. 29, 2014, and has the title “Book Review: ‘Dr. Mütter’s Marvels’ by Cristin O’Keefe Aptowicz.”)

The book under review is:
Aptowicz, Cristin O’Keefe. Dr. Müt­ters Marvels: A True Tale of Intrigue and Innovation at the Dawn of Modern Medicine. New York: Gotham Books, 2014.

U.S. Patents and Start-Ups Fall When We Exclude Tech Immigrants

(p. A19) The process of bringing skilled immigrants to the U.S. via H-1B visas and putting them on the path to eventual citizenship has been a political football for at least a decade. It has long been bad news for those immigrants trapped in this callous process. Now the U.S. economy is beginning to suffer, too.
Every year, tens of thousands of disappointed tech workers and other professionals give up while waiting for a resident visa or green card, and go home–having learned enough to start companies that compete with their former U.S. employers. The recent historic success of China’s Alibaba IPO is a reminder that a new breed of companies is being founded, and important innovation taking place, in other parts of the world. More than a quarter of all patents filed today in the U.S. bear the name of at least one foreign national residing here.
The U.S. no longer has a monopoly on great startups. In the past, the best and brightest people would come to the U.S., but now they are staying home. In Silicon Valley, according to a 2012 survey by Duke and Stanford Universities and the University of California at Berkeley, the percentage of new companies started by foreign-born entrepreneurs has begun to slide for the first time–down to 43.9% during 2006-12, from 52.4% during 1995-2005.

For the full commentary, see:
MICHAEL S. MALONE. “OPINION; The Self-Inflicted U.S. Brain Drain; Up to 1.5 million skilled workers are stuck in immigration limbo. Many give up and go home.” The Wall Street Journal (Thurs., OCT. 16, 2014): A19.
(Note: the online version of the commentary has the date OCT. 15, 2014.)

The 2012 survey is discussed further in:
Wadhwa, Vivek, AnnaLee Saxenian, and F. Daniel Siciliano. “Then and Now: America’s New Immigrant Entrepreneurs, Part VII.” Ewing Marion Kauffman Foundation, October 2012.

An in-depth discussion of the issues raised by Malone can be found in:
Wadhwa, Vivek. The Immigrant Exodus: Why America Is Losing the Global Race to Capture Entrepreneurial Talent. pb ed. Philadelphia, PA: Wharton Digital Press, 2012.